In a far future, Earth had already been visited by an alien race called the Sominids, who came here for the express purpose of drinking and having sex with everyone they could. When one of their infamous parties resulted in the moon being cut in half, and killing everyone who happened to live there, they quietly left. Their encounter with the Sominids had taught the human race many things, primarily that faster than light travel did not exist. Denied the stars, the human race began to dwindle in numbers and terminate all of their space programs.
A thousand years after that, a scientist named Edward Q. Rohta circumvented anti-AI laws, laws which had been on the books for millennia, by creating organic creatures to provide manual labor. Instead of dying after ten years, as promised in the company brochure, they would develop flu-like symptoms and go into hiding. Eventually, fed up with the mistreatment they suffered at the hands of humans, they rose up and killed every man, woman, and child on the planet.
This is the story of what happens next.